Systematic Review of COVID-19 Prognostic Scores

18.12.2023 A new analysis in ORCHESTRA  looks at composition, outcomes, risk of bias, and validation of COVID-19 prognostic scores. The objective was to identify COVID-19 scores for daily clinical care, provide an effective overview for decision-makers, and pave the way for future pandemic preparedness.

 

Among the analysed scores, most had some source of bias. The results unfortunately indicated heterogeneous quality and predictor selection, with only five scores featuring a low risk of bias. Among those, based on the number and heterogeneity of validation studies, only the 4C Mortality Score can be recommended for clinical application. Some promising scores for severity prognostication lack sufficient validation so far.

 

A graphical abstract of the paper – including best-practices for scores – can be found below and for download here in better resolution: Graphical Abstract (pdf)

 

Read the full article here: https://doi.org/10.1093/cid/ciad618