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Systematic Review of COVID-19 Prognostic Scores

Systematic Review of COVID-19 Prognostic Scores

18.12.2023 A new analysis in ORCHESTRA  looks at composition, outcomes, risk of bias, and validation of COVID-19 prognostic scores. The objective was to identify COVID-19 scores for daily clinical care, provide an effective overview for decision-makers, and pave the way for future pandemic preparedness.

 

Among the analysed scores, most had some source of bias. The results unfortunately indicated heterogeneous quality and predictor selection, with only five scores featuring a low risk of bias. Among those, based on the number and heterogeneity of validation studies, only the 4C Mortality Score can be recommended for clinical application. Some promising scores for severity prognostication lack sufficient validation so far.

 

A graphical abstract of the paper – including best-practices for scores – can be found below and for download here in better resolution: Graphical Abstract (pdf)

 

Read the full article here: https://doi.org/10.1093/cid/ciad618

 

 

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ORCHESTRA has received funding from the European Union’s Horizon 2020
research and innovation programme under grant agreement No 101016167.

Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2 Pandemic
EU Call: H2020-SC1-PHE-CORONAVIRUS-2020-2-RTD
Start date: 1 December 2020   End date: 30 November 2024
Coordinated by: UNIVERSITA DEGLI STUDI DI VERONA

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