When analysing the following charts please consider the following:

1. The graphics show the state at the end of the reporting period of this project (all were updated on Nov 29 2024).

2. Most patients do not „go“ through the follow up visits step by step, starting with 3 month follow-up, then 6 month follow-up etc. as you would expect. ORCHESTRA consists of many heterogeneous cohorts with partly different visit structures. Recruitment can be challenging due to different circumstances, which can cause differences in visit timing.

3. Due to the fact that the reporting period began later than the actual start of patient recruitment, which also varies between the different cohorts, you can see stagnating visit figures in some cases as well as higher visit figures from the start in others.